1. Purpose:To study the effect of inhibition of telomerase activity and cell cycle by transcriptase telomerase inhibitors (3′ azido 3′ deoxythymidine, AZT) on squamous cell carcinoma of tongue in vitro. 目的 :研究舌癌细胞经端粒酶抑制剂 (3′ 叠氮 3′ 脱氧胸腺核苷 ,AZT)处理后端粒酶活性和细胞周期的变化情况。
2. OBJECTIVE To improve the synthesis methods of vidarabine monophosphate. 目的改进单磷酸阿糖腺苷的合成工艺。
3. METHODS Vidarabine monophosphate was synthesized by vidarabine phosphorylation directly in the present of pyridine and acetonitrile. The pure products were obtained by crystallization. 方法直接以阿糖腺苷为原料,对其进行磷酸化,经过精制纯化,得到单磷酸阿糖腺苷。
4. Nowadays several kinds of natural bitterness inhibitors have been discovered including certain cinnamic acid derivatives, adenosine monophosphate, phosphatidic acid, etc. 目前已发现多种天然的苦味抑制剂,如苯乙烯酸衍生物、单磷酸腺苷、磷脂酸等。
5. Cytidine 5'-monophosphate, disodium salt hydrate, … 可尼定-5'-单磷酸盐二钠水合物;