deal with 既可指处理具体事情，也可指处理或解决具有抽象意义的问题。
cope with 指成功地处理或对付更为重大，更为严重的问题或事物。
dispose of 与deal with同义，普通用法。
manage 指处理日常事务与工作，也可指经营管理。
handle 从原义“手柄”，转引申为作“处理”解时，其内涵是管理和操纵。
参考例句
1. He was handling his toy all the morning. 整个上午他一直在玩着他的玩具。
2. Who can best handle the problem? 谁能将问题处理得最好？
3. To handle others, use your heart. 要指挥别人，用你的心灵。
英英解释
n.
1. the appendage to an object that is designed to be held in order to use or move it
2. be in charge of, act on, or dispose of
3. interact in a certain way
4. deal with verbally or in some form of artistic expression
5. touch, lift, or hold with the hands
6. handle effectively
7. show and train
